๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

โœ Scribed by Block, Michelle L.; Zecca, Luigi; Hong, Jau-Shyong

Book ID
109962342
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
528 KB
Volume
8
Category
Article
ISSN
1471-0048

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## Abstract Microgliaโ€derived superoxide is critical for the inflammationโ€induced selective loss of dopaminergic (DA) neurons, but the underlying mechanisms of microglial activation remain poorly defined. Using neuronโ€glia and microgliaโ€enriched cultures from mice deficient in the MAC1 receptor (MA