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Microfluidic Rheometer for Characterization of Protein Unfolding and Aggregation in Microflows

✍ Scribed by Sungyoung Choi; Je-Kyun Park

Book ID
104593422
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
295 KB
Volume
6
Category
Article
ISSN
1613-6810

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✍ Erinc Sahin; Adeola O. Grillo; Melissa D. Perkins; Christopher J. Roberts πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 418 KB

Changes in protein-protein interactions, protein unfolding, and nonnative aggregation were assessed for a series of human IgG1 antibodies as a function of pH and solution ionic strength (I). Unfolding transitions were characterized with differential scanning calorimetry. Protein-protein interactions