Microemulsions as topical delivery vehic
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M.R. Gasco; M. Gallarate; M. Trotta; L. Bauchiero; E. Gremmo; O. Chiappero
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Article
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1989
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Elsevier Science
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English
⚖ 512 KB
The topical administration of timolol as an ion-pair with octanoate was achieved by use of an oil-in-water microemulsion containing lecithin as a surfactant. The microemulsion, a solution of the ion-pair and a solution of timolol alone were instilled in the conjunctival sac of rabbits. A rapid metho