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Microemulsions as transdermal drug delivery vehicles

✍ Scribed by Anna Kogan; Nissim Garti


Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
736 KB
Volume
123-126
Category
Article
ISSN
0001-8686

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The topical administration of timolol as an ion-pair with octanoate was achieved by use of an oil-in-water microemulsion containing lecithin as a surfactant. The microemulsion, a solution of the ion-pair and a solution of timolol alone were instilled in the conjunctival sac of rabbits. A rapid metho

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The aim of this study was to investigate the dermal administration of a highly hydrophilic model drug, diphenhydramine (DPH), in colloidal systems with an aqueous colloidal phase in the presence of a glycolipid (GL) as a penetration modifier. Dermal penetration of DPH, GL, and isopropylpalmitate (IP