Development of a novel HPLC-MS/MS method
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Quan-long Zhang; Jin-Hong Hu; Quan-Gang Zhu; Feng-Qian Li; Ji-Yong Liu; Dan Wang
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Article
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2009
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John Wiley and Sons
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English
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## Abstract A sensitive and selective LCโMS/MS method was developed and validated for the determination of aconitine in microdialysate and rat plasma. Extraction of plasma sample was conducted by use of 1% trichloracetic acid and acetonitrile solution with 10 ng/mL internal standard (propafenone) s