Microdialysis assessment of the impact of (+)3,4-methylenedioxymethamphetamine, cocaine, and cocaethylene on serotonergic neurons

Examination of the action of 3,4-methyle

Examination of the action of 3,4-methylenedioxymethamphetamine on rat A10 dopamine neurons

✍ Andrew N. Gifford; Yoshio Minabe; Alon Toor; Rex Y. Wang; Charles R. Ashby Jr. 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 655 KB

Extracellular single cell recording was used to examine the effect of intravenous administration of ( -), (+), and ( 2 )-3,4-methylenedioxymethamphetamine (MDMA) on A10 dopamine (DA) neurons in chloral hydrate anesthetized male rats. Both (5)-MDMA and (+)-MDMA inhibited the firing rate of most (79%)