Microdensitometric measures of cytoplasmic RNA and total protein in pyramidal neurons of the insular cortex and midfrontal gyrus in patients with Alzheimer's disease

Occurrence of the diffuse amyloid β-prot

Occurrence of the diffuse amyloid β-protein (Aβ) deposits with numerous Aβ-containing glial cells in the cerebral cortex of patients with Alzheimer's disease

✍ Haruhiko Akiyama; Hiroshi Mori; Takaomi Saido; Hiromi Kondo; Kenji Ikeda; Patric 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 697 KB

Diffuse amyloid beta-protein (Abeta) deposits with numerous glial cells containing C-terminal Abeta fragments occur in the cerebral cortex of patients with Alzheimer's disease. By using a panel of antibodies specific for various epitopes in the Abeta peptide, we have investigated the immunohistochem