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Microdegradation procedure for radioactive peptide ergot alkaloids

✍ Scribed by G. Basmadjian; H. G. Floss


Publisher
John Wiley and Sons
Year
1971
Tongue
English
Weight
555 KB
Volume
60
Category
Article
ISSN
0022-3549

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✦ Synopsis


Radioactivity determinations were carried out in a Beckman LS 100 liquid scintillation spectrometer, using 10 ml. of a toluene scintillator solution (7 g. 2,5-diphenyloxazole and 0.3 g. dirnethyl-l,Cbis[2-(4methyI-5-phenyloxazolyl)]benzene/I000 ml. toluene) for compounds dissolved in organic solvents or 10 ml. of Bray's solution Abstract c1 A degradation procedure for **C-Iabeled peptide ergot alkaloids is described; it allows the determination of the specific activities of all the products obtained in the hydrolysis of these alkaloids from a sample of not more than 10 umoles.

(7) for aqueous samples.

counting the sample after the addition of a known amount of toluene-14C as internal standard. Colorimetric determinations were Keyphrases Ergot alkaloids, radioactive peptides-biosynthesis,

The counting efficiency for each sample was determined by redegradation, isotope distribution 0 Peptide ergot alkaloids, radiolabeled-degradation, distribution TLC-separation, analysis