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Microcystin-LR induced cellular effects in mammalian and fish primary hepatocyte cultures and cell lines: A comparative study

✍ Scribed by Daniela Alina Boaru; Nicolae Dragoş; Kristin Schirmer


Book ID
108287264
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
365 KB
Volume
218
Category
Article
ISSN
0300-483X

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The influence of cell density and epidermal growth factor (EGF) on the expression and inducibility of cytochrome P450 (CYP) genes of the CYP3A and CYP1A families in adult human hepatocytes in primary culture has been evaluated. Only when cultured at subconfluence and in the presence of EGF did hepat