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Microbiological transformations of fusidane-type antibiotics a correlation between fusidic acid and helvolic acid

✍ Scribed by W. von Daehne; H. Lorch; W.O. Godtfredsen

Publisher: Elsevier Science
Year: 1968
Tongue: French
Weight: 248 KB
Volume: 9
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)72771-7

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✦ Synopsis

The structural work on the antibiotic helvolic acid culminated recently when Okuda et al.'

proposed formula I on the basis of convincing chemical and spectroscopic evidence. According to this proposal the compound contains the same framework as fusidic acid (II)2a'b and thus belongs

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