Microbiological transformations: Hydroxylation of non activated carbons in bridged bicyclic amides.

✍ Scribed by R. Furstoss; A. Archelas; B. Waegell; J. Le Petit; L. Deveze

• Book ID: 104213020
• Publisher: Elsevier Science
• Year: 1980
• Tongue: French
• Weight: 273 KB
• Volume: 21
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)71430-4

✦ Synopsis

The regio and stereoselectivity of the hydroxylations are described and the geometric requirements of the enzyme site are discussed.

Biohydroxylations are one aspect of the very interesting applications of enzymes to synthetic chemistry, as they allow regio, stereo and even enantioselective fonctionalisation of non activated carbons (1). Such reac-