✦ LIBER ✦

Microbiological transformations 40. Use of fungal epoxide hydrolases for the synthesis of enantiopure alkyl epoxides

✍ Scribed by Philippe Moussou; Alain Archelas; Roland Furstoss

Book ID: 104208307
Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 592 KB
Volume: 54
Category: Article
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(97)10394-5

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✦ Synopsis

The enantiosolective biohydrolyses of various substituted alkyl-epoxides using seven different fungi are described. These strains were used to achieve the preparation of these alkyl epoxides in high enantiomeric purity. A combined chemoenzymatic process is also described, allowing to enhance the overall yield of such an approach.

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