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Microbiological Dehydroxylation of Cholic Acid

✍ Scribed by HAYAKAWA, SHOHEI; KUROKAWA, KATSUMI


Book ID
109630211
Publisher
Nature Publishing Group
Year
1963
Tongue
English
Weight
120 KB
Volume
199
Category
Article
ISSN
0028-0836

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Reduction of the trioxime derivative of dehydrocholic acid methyl ester with NaBH4-TiCI4 yielded triamine-derivatives of cholic acid. The major product from the reduction was the 3o~,7Β’x, 12Β’x diastereomer. Stereochemistry of the reduction products was determined via NMR spectroscopy and Xray crysta