Microbial Transformations of 6α- and 6β-Eudesmanolides by Rhizopus nigricans Cultures
✍ Scribed by García, Yolanda; García-Granados, Andrés; Martínez, Antonio; Parra, Andrés; Rivas, Francisco; Arias, José María
- Book ID
- 126960283
- Publisher
- American Chemical Society
- Year
- 1995
- Tongue
- English
- Weight
- 772 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0163-3864
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Epimerization at C-6 of polyfimctionalized 6a-eudesmanolides was achieved by chemical means, to obtain 6ikwdesmanolides and, after rearrangement, 6p-guaianolides. The epimerization process consists of the LiAU$ reduction of a 6a-lactone, selective pmtection of the hydroxymethylene group at C-12, oxi