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Microbial Antigen Sensitization and Colitis in Chronic Granulomatous Disease and Hyper IgE Syndrome

✍ Scribed by Yu, J.E.; DeRavin, S.S.; Uzel, G.; Mayer, L.F.; Targan, S.R.; Malech, H.L.; Holland, S.M.; Cunningham-Rundles, C.

Book ID: 119282739
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 42 KB
Volume: 125
Category: Article
ISSN: 1097-6825
DOI: 10.1016/j.jaci.2009.12.065

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## Background: Chronic granulomatous disease (cgd) is a rare inherited immunodeficiency disorder characterized by inability of phagocytes to kill certain bacteria and fungi. histology from colon biopsies of cgd patients have shown the presence of inflammation and granulomas, almost indistinguishabl