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Microbial and xanthine dehydrogenase inhibitory activity of some flavones

✍ Scribed by Khobragade, C. N.; Bodade, Ragini G.; Shinde, M. S.; Jaju, Deepa R.; Bhosle, R. B.; Dawane, B. S.


Book ID
121845205
Publisher
Informa plc
Year
2008
Tongue
English
Weight
144 KB
Volume
23
Category
Article
ISSN
1475-6366

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A series (C1-C12) of alkyl gallates was examined for their effects on the activity of xanthine oxidase. Octyl (C8), decyl (C10), and dodecyl (C12) gallates competitively inhibited uric acid formation generated by xanthine oxidase, and the inhibition increased upon increasing the alkyl chain length.