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Microalgae as a source of stable isotopically labeled compounds

✍ Scribed by Paul W. Behrens; Valerie J. Sicotte; Jacques Delente


Publisher
Springer
Year
1994
Tongue
English
Weight
746 KB
Volume
6
Category
Article
ISSN
0378-1909

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## Abstract Stable isotopically labelled (SIL) versions of Glimepiride **1** (10 steps, 11% overall yield), a blood glucose lowering drug, and Melagatran **13** (9 steps, 17% overall yield), an anticoagulant with similar uses to warfarin, were synthesized as internal standards for LCMS assays. Modi