Stable isotopic labelling of heterocycli
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Andrew J. Burton; Alan H. Wadsworth
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Article
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2007
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John Wiley and Sons
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French
β 111 KB
## Abstract Stable isotopically labelled (SIL) versions of Glimepiride **1** (10 steps, 11% overall yield), a blood glucose lowering drug, and Melagatran **13** (9 steps, 17% overall yield), an anticoagulant with similar uses to warfarin, were synthesized as internal standards for LCMS assays. Modi