Micro and Nanotechnology in Vaccine Development

✍ Scribed by Mariusz Skwarczynski, Istvan Toth

• Publisher: Elsevier
• Year: 2017
• Tongue: English
• Leaves: 437
• Series: Micro and Nano Technologies
• Edition: 1
• Category: Library

✦ Synopsis

This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress.

MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles.

• Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development
• Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development
• Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines

✦ Table of Contents

Content:
Front matter,Copyright,List of Contributors,IntroductionEntitled to full textChapter One - The Growing Influence of Nanotechnology in Our Lives, Pages 1-20, A. Ranzoni, M.A. Cooper
Chapter Two - Nanotechnology in Medical Research, Pages 21-45, F.M. Mansfeld, T.P. Davis, M. Kavallaris
Chapter Three - Introduction to Vaccines and Vaccination, Pages 47-62, A.C.I. Depelsenaire, M.A.F. Kendall, P.R. Young, D.A. Muller
Chapter Four - Overview of the Immune System, Pages 63-81, S. Kellie, Z. Al-Mansour
Chapter Five - The Role of Antigen Presentation and Innate Immunity During Immune Induction by Particulate Antigens, Pages 83-98, M.R. Neeland, M.J. de Veer, J.-P.Y. Scheerlinck
Chapter Six - Inflammatory/Noninflammatory Adjuvants and Nanotechnology—The Secret to Vaccine Design, Pages 99-125, K.L. Wilson, S.D. Xiang, M. Plebanski
Chapter Seven - Vaccine Adjuvant Nanotechnologies, Pages 127-147, T. Barclay, N. Petrovsky
Chapter Eight - Nanoparticle-Based Peptide Vaccines, Pages 149-170, Y. Fujita, H. Taguchi
Chapter Nine - Microparticles and Nanoparticles for Cancer-Targeting Vaccines, Pages 171-183, A.S. Morris, A. Wongrakpanich, S.M. Geary, A.K. Salem
Chapter Ten - Polymer-Based Nanoparticles as Modern Vaccine Delivery Systems, Pages 185-203, L. Lambricht, C. Peres, H. Florindo, V. Préat, G. Vandermeulen
Chapter Eleven - Virus-Like Particles, Pages 205-219, M. Tagliamonte, M.L. Tornesello, F.M. Buonaguro, L. Buonaguro
Chapter Twelve - Liposomes as a Vaccine Delivery System, Pages 221-239, N. Marasini, K.A. Ghaffar, M. Skwarczynski, I. Toth
Chapter Thirteen - Nanomaterials Based on Lipids for Vaccine Development, Pages 241-257, A.M. Carmona-Ribeiro
Chapter Fourteen - Microparticles for Vaccine Delivery, Pages 259-278, N. Mody, R. Sharma, S. Dubey, S.P. Vyas
Chapter Fifteen - Nasal Vaccine Delivery, Pages 279-301, M. Ramvikas, M. Arumugam, S.R. Chakrabarti, K.S. Jaganathan
Chapter Sixteen - Toward Mucosal DNA Delivery: Structural Modularity in Vaccine Platform Design, Pages 303-326, P. Holla, M.A. Baikoghli, P. Soonsawad, R.H. Cheng
Chapter Seventeen - Nano- and Microtechnology in Skin Delivery of Vaccines, Pages 327-341, N. Dang, T.Y. Liu, T.W. Prow
Chapter Eighteen - Nanopatches for Vaccine Delivery, Pages 343-356, M.L. Crichton, M.A.F. Kendall
Chapter Nineteen - Rationale for Pulmonary Vaccine Delivery: Formulation and Device Considerations, Pages 357-371, I. Saleem, K. Petkar, S. Somavarapu
Chapter Twenty - Nanotoxicology and Nanovaccines, Pages 373-392, G.M. Mortimer, R.F. Minchin
Chapter Twenty One - Regulatory Development of Nanotechnology-Based Vaccines, Pages 393-410, H.F. Florindo, J. Lopes, L.C. Silva, M.L. Corvo, M.B. Martins, R. Gaspar
Chapter Twenty Two - Commercial Aspects of Vaccine Development, Pages 411-421, J. Halliday
Subject Index, Pages 423-441

✦ Subjects

Vaccines;Vaccines;pharmacology