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Michaelis-Menten for single enzyme molecules

โœ Scribed by Doerr, Allison


Book ID
109935835
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
71 KB
Volume
3
Category
Article
ISSN
1552-4450

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The total quasi-steady state approximation (tQSSA) for the irreversible Michaelis-Menten scheme is derived in a consistent manner. It is found that self-consistency of the initial transient guarantees the uniform validity of the tQSSA, but does not guarantee the validity of the linearization in the