Michael Reactions of α-Unsubstituted Trisubstituted 1H-Pyrroles

✍ Scribed by Rainer Lüönd; Reinhard Neier

• Book ID: 102859311
• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: German
• Weight: 730 KB
• Volume: 74
• Category: Article
• ISSN: 0018-019X
• DOI: 10.1002/hlca.19910740111

✦ Synopsis

Abstract

To obtain stable derivatives of α‐unsubstituted pyrroles, the reaction of the test pyrrole 9 with a series of chalcones 14a–h were studied. Michael adducts 16b–h could be isolated. In order to synthesize coloured derivatives, the reaction of different pyrroles 9, 21, 23, and 25 with diphenylpropynone 19 was investigated. In these cases, too, Michael‐addition products were formed. The intense absorption band around 400 nm makes the identification of these derivatives easy.