Micellar nanomedicine of human neuropeptide Y

✍ Scribed by Antonina Kuzmis; Sok Bee Lim; Esha Desai; Eunjung Jeon; Bao-Shiang Lee; Israel Rubinstein; Hayat Önyüksel

• Publisher: Elsevier Science
• Year: 2011
• Tongue: English
• Weight: 925 KB
• Volume: 7
• Category: Article
• ISSN: 1549-9634
• DOI: 10.1016/j.nano.2011.01.004

✦ Synopsis

From the clinical editor:

Human neuropeptide y (npy) regulates a multitude of physiological functions and could be amenable to therapeutic manipulations, which is currently limited by its short half life. self-association of npy with spherically stabilized micelles (ssm) protects and stabilizes the peptide in active monomeric conformation, thereby amplifying its bioactivity in vitro, enabling future therapeutic considerations.