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Mice lacking inducible nitric oxide synthase show strong resistance to anti-Fas antibody-induced fulminant hepatitis

✍ Scribed by BaoJun Chang; Manabu Nishikawa; Eisuke Sato; Masayasu Inoue


Book ID
117042419
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
452 KB
Volume
411
Category
Article
ISSN
0003-9861

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Lack of inducible nitric oxide synthase
✍ Ghazaleh Aram; James J. Potter; Xiaopu Liu; Michael S. Torbenson; Esteban Mezey πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 696 KB

The role of nitric oxide (NO) in liver injury and fibrosis is unclear. The purpose of this study was to determine whether inducible NO synthase deficiency (iNOS(-/-)) affects liver injury and fibrosis produced in mice by chronic carbon tetrachloride (CCl(4)) administration. Wild-type (WT) or iNOS(-/