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Mice deficient in invariant-chain and MHC class II exhibit a normal mature B2 cell compartment

✍ Scribed by Rene´ Maehr; Manfred Kraus; Hidde L. Ploegh


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
217 KB
Volume
34
Category
Article
ISSN
0014-2980

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The major histocompatibility (MHC) class II genes encode cell surface proteins that bind antigenic peptide for presentation to T-cells. The class II proteins are expressed constitutively on B-cells and EBV-transformed B-cells, and are inducible by IFN-y on a wide variety of cell types. Retinoblastom