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Mice and rats are sensitized to the proconvulsant action of a benzodiazepine-receptor inverse agonist (FG 7142) following a single dose of lorazepam

โœ Scribed by Richard G. Lister; David J. Nutt


Book ID
118871627
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
270 KB
Volume
379
Category
Article
ISSN
0006-8993

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Effects of a single or repeated administ
โœ S. C. Stanford; H. A. Baldwin; S. E. File ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 925 KB

We have reported previously an increase in the number of beta-adrenoceptors in mouse cerebral cortex 7 days after kindling of seizures by repeated once-daily administration of the benzodiazepine receptor inverse agonist, FG7142. In subsequent experiments, an even larger increase in beta-adrenoceptor