๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

MHC haplotypes and CYP21/C4 gene organisation in 21-hydroxylase deficient families from three European populations

โœ Scribed by Sinnott, P.J.; Tassabehji, M.; Costigan, C.; Livieri, C.; Dyer, P.A.; Strachan, T.


Book ID
122628790
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
85 KB
Volume
32
Category
Article
ISSN
0198-8859

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Extended MHC haplotypes and CYP21/C4 gen
โœ Paul J. Sinnott; Colm Costigan; Philip A. Dyer; Rodney Harris; Tom Strachan ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Springer ๐ŸŒ English โš– 845 KB

We have analysed fifteen classical 21-hydroxylase deficiency families from throughout Southern Ireland and report the serologically defined HLA-A, HLA-B, HLA-Cw, HLA-DR, C4A and C4B polymorphisms that characterize the inferred disease haplotypes. Additionally, we have used a combination of short and

CYP21/C4 gene organisation in Italian 21
โœ Paul J. Sinnott; Chiara Livieri; Maurizio Sampietro; Massimo Marconi; Rodney Har ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 864 KB

A total of 33 Italian 21-hydroxylase (21-OH) deficiency families were investigated using a combination of short and long range restriction mapping of the CYP21/C4 gene cluster. The analyses revealed that large-scale length polymorphism in this gene cluster strictly conformed to a compound variable n