✦ LIBER ✦

MGMT-methylation & IDH-1-mutation as prognostic factors in high-grade gliomas

✍ Scribed by Alonso Sánchez, D.; Matallanas, M.; Balbin, M.; Centeno, I.; Perez-payo, P.; Canteli, M.; Martínez, P.

Book ID: 123212774
Publisher: Wielkopolskie Centrum Onkologii
Year: 2013
Tongue: Polish
Weight: 54 KB
Volume: 18
Category: Article
ISSN: 1507-1367
DOI: 10.1016/j.rpor.2013.03.733

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Prognostic or predictive value of MGMT p

Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation

✍ Wick, W.; Meisner, C.; Hentschel, B.; Platten, M.; Schilling, A.; Wiestler, B.; 📂 Article 📅 2013 🏛 Lippincott Williams and Wilkins 🌐 English ⚖ 399 KB

572 SOCS1 Methylation is Associated to M

572 SOCS1 Methylation is Associated to MGMT Methylation and IDH1 Mutation in Gliomas

✍ E. Irles Vidal; C. Alenda; C. Egoavil; A. Garcia-Martinez; E. Hernandez-Illan; A 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 55 KB

524 MGMT Gene Promoter Methylation by Py

524 MGMT Gene Promoter Methylation by Pyrosequencing and IDH1 Mutation by PNA-mediated PCR Clamping in Gliomas

✍ D. Kim; Y. Kim; K. Kim; Y. Song; Y. Choi; S. Choi 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 58 KB

Significance of complete 1p/19q co-delet

Significance of complete 1p/19q co-deletion, IDH1 mutation and MGMT promoter methylation in gliomas: use with caution

✍ Boots-Sprenger, Sandra H E; Sijben, Angelique; Rijntjes, Jos; Tops, Bastiaan B J 📂 Article 📅 2013 🏛 Nature Publishing Group 🌐 English ⚖ 584 KB

Evaluation status and prognostic signifi

Evaluation status and prognostic significance of O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in pediatric high grade gliomas

✍ Francesca R. Buttarelli; Maura Massimino; Manila Antonelli; Libero Lauriola; Pao 📂 Article 📅 2010 🏛 Springer 🌐 English ⚖ 289 KB

IDH1 mutations at residue p.R132 (IDH1R1

IDH1 mutations at residue p.R132 (IDH1R132) occur frequently in high-grade gliomas but not in other solid tumors

✍ Fonnet E. Bleeker; Simona Lamba; Sieger Leenstra; Dirk Troost; Theo Hulsebos; W. 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 196 KB

Systematic sequence profiling of the Glioblastoma Multiforme (GBM) genome has recently led to the identification of somatic mutations in the isocitrate dehydrogenase 1 (IDH1) gene. Interestingly, only the evolutionarily conserved residue R132 located in the substrate binding site of IDH1 was found m