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Mg2+ mimicry in the promotion of group I ribozyme activities by aminoglycoside antibiotics

โœ Scribed by Yijia Bao; David L. Herrin

Book ID
116292801
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
213 KB
Volume
344
Category
Article
ISSN
0006-291X

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Activation of the ฮฑ2ฮฒ1 integrin-mediated
Activation of the ฮฑ2ฮฒ1 integrin-mediated malignant phenotype on type I collagen in pancreatic cancer cells by shifts in the concentrations of extracellular Mg2+ and Ca2+
โœ John J. Grzesiak; Michael Bouvet ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 755 KB

## Abstract The authors have previously demonstrated that ฮฑ~2~ฮฒ~1~ integrinโ€mediated pancreatic cancer cell adhesion to Type I collagen is Mg^2+^โ€dependent, inhibited by Ca^2+^, and that this integrin, purified from cell lysates using Type Iโ€collagenโ€sepharose in Mg^2+^, can be eluted with Ca^2+^.