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Mg2+-mediated binding of 6-Substituted quinolones to DNA: relevance to biological activity

โœ Scribed by Claudia Sissi; Magda Andreolli; Violetta Cecchetti; Arnaldo Fravolini; Barbara Gatto; Manlio Palumbo


Book ID
108480654
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
190 KB
Volume
6
Category
Article
ISSN
0968-0896

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๐Ÿ“œ SIMILAR VOLUMES


Intercalation binding of 6-substituted n
โœ Harry P. Hopkins Jr.; Yang Ming; W. David Wilson; David W. Boykin ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Wiley (John Wiley & Sons) ๐ŸŒ English โš– 758 KB

## Abstract Nโ€(3โ€dimethylaminopropyl) naphtho [2, 1โ€__b__] thiopheneโ€4โ€carboxamide and the 6โ€substituted methoxy, methyl, fluoro, chloro, bromo, trifluoromethyl, and cyano derivatives have been shown to bind to DNA via intercalation with binding constants in the 35โ€“900 ร— 10^3^ range at 25ยฐC, pH 7,