Mg2+ and Excitable Membranes

✍ Scribed by Professor Piergiorgio Strata, Professor Emilio Carbone (auth.)

Publisher: Springer-Verlag Berlin Heidelberg
Year: 1991
Tongue: English
Leaves: 152
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This volume presents the most recent research findings on the key role played by Mg2+ in the regulation of ion channels in excitable tissue. Contributions describe the multiple actions exerted by Mg2+ on the different types on ion channels controlling nerve and cardiac cell activity. Recent developments in the detection of single ion channel activity provide important insights into the mechanisms of action of Mg2+ at the channel level.

✦ Table of Contents

Front Matter....Pages I-IX
Use of Ion Selective Microelectrodes to Measure Intracellular Free Mg 2+ ....Pages 1-19
Voltage-Gated Ionic Channels: Diversity and Modulation by Mg 2+ ....Pages 21-31
ATP-Dependent K + Channels of Excitable Membranes....Pages 33-49
Voltage-Dependent Blockage of Cardiac Inwardly Rectifying K + Channels by Internal Mg 2+ ....Pages 51-70
Regulation of the Voltage-Gated Ca 2+ Current by Intracellular Free Mg 2+ Studied by Internal Perfusion of Single Cardiac Myocytes....Pages 71-96
Blockage of Neuronal Low-Threshold Ca 2+ Channels by Extracellular Mg 2+ ....Pages 97-104
Dual Block by Mg 2+ of the N -Methyl-D-Aspartate-Activated Channel....Pages 105-118
Excess Mg 2+ and Central Nervous System Metabolism....Pages 119-123
Mg 2+ in Neurotrauma: Its Role and Therapeutic Implications....Pages 125-145
Back Matter....Pages 147-150

✦ Subjects

Neurosciences; Human Physiology

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