Mg and Zn mediated allylation of imines with allyl bromide
โ Scribed by De-Kun Wang; Li-Xin Dai; Xue-Long Hou; Yi Zhang
- Book ID
- 103407021
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 117 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
a b s t r a c t 2-(Alkoxy)propenyl bromides are readily prepared from 1,3-dibromo-2-propanol in a two-step sequence involving hydroxyl protection and sodium hydride-induced dehydrobromination. Indium-mediated allylation of aldehydes, ketones, and sulfonimines with 2-(alkoxy)propenyl bromides furnish
Anomalous syn-diastereoselectivity of indium-mediated coupling of aldehydes with bromides Z-3b and E-3b is reported. The reaction afforded high syn selectivity regardless of the allylic bromide geometry. Preliminary studies on the enantioselective indium-mediated allylation were attempted and found