✦ LIBER ✦

Mevalonate is essential for growth of porcine and human vascular smooth muscle cells in vitro

✍ Scribed by G. Rogler; K. J. Lackner; G. Schmitz

Publisher: Springer
Year: 1995
Tongue: English
Weight: 912 KB
Volume: 90
Category: Article
ISSN: 0300-8428
DOI: 10.1007/bf00788536

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Nicotinic and PDGF-receptor function are

Nicotinic and PDGF-receptor function are essential for nicotine-stimulated mitogenesis in human vascular smooth muscle cells

✍ Ivo A. Pestana; Roberto I. Vazquez-Padron; Abdelouahab Aitouche; Si M. Pham 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 211 KB

## Abstract Cigarette smoking is implicated in the formation of occlusive vascular diseases. Nicotine's role in this process is incompletely understood. Nicotine's effect on human aortic vascular smooth muscle cells (HaVSMC) and the role of the nicotinic receptor (nAChR), platelet‐derived growth fa

Statins inhibit in vitro calcification o

Statins inhibit in vitro calcification of human vascular smooth muscle cells induced by inflammatory mediators

✍ Akane Kizu; Atsushi Shioi; Shuichi Jono; Hidenori Koyama; Yasuhisa Okuno; Yoshik 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB 👁 1 views

## Abstract Although lipid‐lowering therapy with 3‐hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors (statins) decreases the progression of coronary artery and aortic valve calcification, the mechanism of action of these drugs to inhibit the calcification process remains unclear. In this stu

Proteasomal degradation of myocardin is

Proteasomal degradation of myocardin is required for its transcriptional activity in vascular smooth muscle cells

✍ Hao Yin; Yulan Jiang; Haijie Li; Jingjing Li; Yu Gui; Xi-Long Zheng 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 799 KB

Myocardin is a transcriptional co-activator of serum response factor (SRF) and can be degraded through ubiquitin-proteasome system. Our preliminary studies unexpectedly revealed that accumulation of myocardin in response to proteasome inhibition by MG132 or lactacystin resulted in decrease of transc

Effects of shear stress on the growth ki

Effects of shear stress on the growth kinetics of human aortic smooth muscle cells in vitro

✍ Maria Papadaki; Larry V. McIntire; Suzanne G. Eskin 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 912 KB

After cardiovascular intervention, smooth muscle cells (SMC) are directly exposed to blood flow and thus their behavior might be affected by fluid hemodynamic forces. The aim of this study was to determine the effect of fluid shear stress on the growth rate of SMC. Human aortic smooth muscle cells (

Differential expression of the keratinoc

Differential expression of the keratinocyte growth factor (KGF) and KGF receptor genes in human vascular smooth muscle cells and arteries

✍ Jeffrey A. Winkles; Gregory F. Alberts; Marcio Chedid; William G. Taylor; Sabina 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 148 KB 👁 2 views

Keratinocyte growth factor (KGF) is a secreted member of the fibroblast growth factor (FGF) family of heparin-binding proteins. Studies reported to date indicate that it functions primarily as an important paracrine mediator of epithelial cell growth and differentiation. KGF appears to act via bindi

COP-1, a member of the CCN family, is a

COP-1, a member of the CCN family, is a heparin-induced growth arrest specific gene in vascular smooth muscle cells

✍ Laurie M. Delmolino; Nancy A. Stearns; John J. Castellot Jr. 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 256 KB

## Abstract Vascular smooth muscle cell (VSMC) hyperplasia is responsible for the failure of 15–30% of vascular surgical procedures such as coronary artery bypass grafts and angioplasties. We and others have shown that heparin suppresses VSMC proliferation in vivo and in cell culture. We hypothesiz