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Metronomic chemotherapy with daily, oral etoposide plus bevacizumab for recurrent malignant glioma: a phase II study

✍ Scribed by Herndon, J E; Marcello, J E; Norfleet, J; Reardon, D A; Desjardins, A; Vredenburgh, J J; Gururangan, S; Sampson, J H; Sathornsumetee, S; McLendon, R E

Book ID
110000229
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
472 KB
Volume
101
Category
Article
ISSN
0007-0920

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## Abstract ## BACKGROUND Although temozolomide is active against recurrent malignant glioma, responses in many patients are modest and short‐lived. Temozolomide may prove more effective in combination with other agents. Therefore, combination oral chemotherapy for these patients is a particularly