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Metrazol kindling in animals differing in sensitivity to the convulsant

✍ Scribed by G. N. Kryzhanovskii; M. N. Karpova; O. Yu. Pankov

Publisher
Springer US
Year
1991
Tongue
English
Weight
288 KB
Volume
112
Category
Article
ISSN
0007-4888

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Sex differences in the sensitivity of CBA mice to convulsions induced by GABA antagonists are age-dependent
✍ Hari Manev; Danka PeričiΔ‡; Suzana AniΔ‡-StojiljkoviΔ‡ πŸ“‚ Article πŸ“… 1987 πŸ› Springer 🌐 English βš– 426 KB

The administration of the GABA-blocking agents picrotoxin and bicuculline to adult (2.5-3 months old) CBA/HZgr mice resulted in the appearance of convulsions, the occurrence and/or lethality of which was greater in males than in females. The latency of picrotoxin-induced convulsions was also shorter