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Metoclopramide kinetics at high-dose infusion rates for prevention of cisplatin-induced emesis

✍ Scribed by Saller, R; Hellenbrecht, D; Briemann, L; Hellstern, A; Hess, H; Mitrou, P; Hodgson, M; Achtert, G; Brockmann, P; Hausleiter, H J

Book ID
109843838
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
345 KB
Volume
37
Category
Article
ISSN
0009-9236

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πŸ“œ SIMILAR VOLUMES

Continuous infusion of high-dose metoclo
Continuous infusion of high-dose metoclopramide: comparison of pharmacokinetically adjusted and standard doses for the control of cisplatin-induced acute emesis
✍ J. M. Brechot; J. P. Dupeyron; C. Delattre; Cl. Chastang; J. P. Laaban; J. Roche πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 461 KB

Metoclopramide was administered by continuous infusion to two groups each of 14 patients on chemotherapy, randomized to receive either doses adjusted to individual pharmacokinetic parameters or doses adjusted as usual to body weight. The mean plasma concentration at the end of the infusion in the ad