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Methylxanthines cause a decrease of prolactin plasma levels in healthy non-pregnant women

✍ Scribed by M. Casas; S. Ferre; J. Rodriguez; F. Jane

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 519 KB
Volume: 4
Category: Article
ISSN: 0885-6222
DOI: 10.1002/hup.470040106

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✦ Synopsis

The effect of different doses of caffeine and theophylline (2,4 and 8 mg/ kg p.0.) on prolactin plasma levels in volunteer non-pregnant women has been analysed. The study of basal serum prolactin levels demonstrated great interindividual variation with a good reproducibility of the basal prolactin pattern for all subjects. We found a slight but significant decrease in prolactin levels following xanthine administration. The possible dopaminergic agonism of xanthines and the consequent social implications are discussed.

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