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Methylthioadenosine phosphorylase inactivation depends on gene deletion in laryngeal squamous cell carcinoma

✍ Scribed by Conde, Laura; Vilaseca, Isabel; Alós, Llucia; Bernal-Sprekelsen, Manuel; Cardesa, Antonio; Nadal, Alfons


Book ID
119834542
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
323 KB
Volume
61
Category
Article
ISSN
0309-0167

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## Abstract Defects in the system controlling the cell cycle can lead an increased proliferation of cancer cells. The aim of our study was to analyze the relationship between genetic changes leading to inactivation of the __CDKN2A__ gene and subsequent alteration of protein expression in squamous c