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Methylprednisolone inhibition of TNF-α expression and NF-kB activation after spinal cord injury in rats

✍ Scribed by Jan Xu; Guangshun Fan; Shawei Chen; Yingji Wu; Xiao Ming Xu; Chung Y. Hsu

Book ID
117387157
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
645 KB
Volume
59
Category
Article
ISSN
0169-328X

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## Experimental allergic encephalomyelitis (EAE), an animal model for multiple sclerosis (MS) , is a demyelinating autoimmune disease of the central nervous system (CNS). The proinflammatory cytokine TNF␣, as an endogenous mediator of inflammation, plays an important role in the pathogenesis of EA