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Methylparaben protects 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells and improved behavioral impairments in mouse model of Parkinson's disease

✍ Scribed by Kopalli, Spandana Rajendra; Noh, Su-Jin; Koppula, Sushruta; Suh, Yoo-Hun


Book ID
120316847
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
836 KB
Volume
34
Category
Article
ISSN
0161-813X

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## Abstract It has been postulated that the pathogenesis of Parkinson's disease (PD) is associated with mitochondrial dysfunction. Rotenone, an inhibitor of mitochondrial complex I, provides models of PD both in vivo and in vitro. We investigated the neuroprotective effect of D‐β‐hydroxybutyrate (b