Methylmercury alters glutamate transport in astrocytes
โ Scribed by Michael Aschner; Chang Ping Yao; Jeffrey W Allen; Kim H Tan
- Book ID
- 117409535
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 300 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0197-0186
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๐ SIMILAR VOLUMES
Glutamate uptake and metabolism was studied in cerebral cortical astrocytes. The expression of the astrocytic glutamate transporter GLAST was found to be stimulated by extracellular glutamate through activation of kainate receptors on the astrocytes. Energy metabolism and ammonia homeostasis are two
## Abstract Wernicke encephalopathy (WE), a neurological disorder caused by thiamine deficiency (TD), is characterized by structural damage in brain regions that include the thalamus and cerebral cortex. The basis for these lesions is unclear, but may involve a disturbance of glutamatergic neurotra