✦ LIBER ✦
Methylierung von 4-Hydroxy-4-(2-piperidyl)-4H-pyrazolo [1,5-a]indol mit Formaldehyd und Ameisensäure. 11. Mitteilung über metallorganische Reaktionen und Folgeprodukte
✍ Scribed by Grety Rihs; Hermann Fuhrer; Adrian Marxer
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- German
- Weight
- 287 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0018-019X
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
In the 10^th^ communication of this series [1] the synthesis of 4‐hydroxy‐4‐(2‐piperidyl)‐4__H__‐pyrazolo[1,5‐a]indole (4) was described (Scheme). Surprisingly enough, methylation of this compound with formaldehyde and formic acid led via ring closure and a subsequent rearrangement to a pentacyclic ketone. By means of ^13^C‐NMR.‐spectroscopy and mass spectroscopy, this ketone could be identified as a indolizino‐pyrazolo‐indole (9). Its structure and configuration were determined by X‐ray structure analysis.