Methylenetetrahydrofolate reductase C677T polymorphism and congenital heart disease: a meta-analysis

✍ Scribed by Nie, Yu; Gu, Haiyong; Gong, Jie; Wang, Jue; Gong, Dingxu; Cong, Xiangfeng; Chen, Xi; Hu, Shengshou

• Book ID: 119969580
• Publisher: Walter de Gruyter GmbH & Co. KG
• Year: 2011
• Tongue: English
• Weight: 944 KB
• Volume: 49
• Category: Article
• ISSN: 1434-6621
• DOI: 10.1515/CCLM.2011.673

✦ Synopsis

Abstract

As a key enzyme in folate metabolism, 5,10-methylenetetrahydrofolate reductase (MTHFR) regulates the homeostasis between DNA synthesis and methylation. Data on the association between the

To assess the relationship between the

The

Our meta-analysis suggests that genotypes for the