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Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and susceptibility to gastric adenocarcinoma in an Italian population

✍ Scribed by Boccia, Stefania; Gianfagna, Francesco; Persiani, Roberto; La Greca, Antonio; Arzani, Dario; Rausei, Stefano; D'Ugo, Domenico; Magistrelli, Paolo; Villari, Paolo; Van Duijn, Cornelia M.; Ricciardi, Gualtiero

Book ID
120248126
Publisher
Informa plc
Year
2007
Tongue
English
Weight
120 KB
Volume
12
Category
Article
ISSN
1354-750X

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Methylenetetrahydrofolate reductase 677C
Methylenetetrahydrofolate reductase 677C/T gene polymorphism, gastric cancer susceptibility and genomic DNA hypomethylation in an at-risk Italian population
✍ Francesco Graziano; Kazuyuki Kawakami; Annamaria Ruzzo; Go Watanabe; Daniele San πŸ“‚ Article πŸ“… 2005 πŸ› John Wiley and Sons 🌐 French βš– 88 KB

## Abstract We performed a case‐control study to examine the relationship between __MTHFR C677T__ gene polymorphism (__MTHFR677C/T__) and gastric cancer susceptibility in at‐risk populations in central Italy. To explore genomic DNA hypomethylation as a potential etiologic mechanism, this phenomenon