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Methylation status within exon 3 of the c-myc gene as a prognostic marker in myeloma and leukaemia

✍ Scribed by Janet Stephenson; Recep Akdag; Namik Ozbek; Ghulam J. Mufti

Book ID: 113239708
Publisher: Elsevier Science
Year: 1993
Tongue: English
Weight: 276 KB
Volume: 17
Category: Article
ISSN: 0145-2126
DOI: 10.1016/0145-2126(93)90014-c

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## Abstract ## BACKGROUND Silencing of tumor suppressor genes (TSG) by aberrant methylation (referred to as __methylation__) contributes to the pathogenesis of various human malignancies. However, little is known about the methylation of known and putative TSGs in monoclonal gammopathies. Thus, th