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Methylation Status of Genes in Non-Neoplastic Mucosa From Patients With Ulcerative Colitis-Associated Colorectal Cancer

✍ Scribed by Garrity-Park, Megan M; Loftus, Edward V; Sandborn, William J; Bryant, Sandra C; Smyrk, Thomas C


Book ID
111912193
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
171 KB
Volume
105
Category
Article
ISSN
0002-9270

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Background: Although DNA methylation of colonic mucosa in ulcerative colitis (UC) has been suggested, the majority of published reports indicate the correlation between methylation of colon mucosa and occurrence of UC-related dysplasia or cancer without considering the mucosal inflammatory status. T