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Methylation of the human papillomavirus-18 L1 gene: A biomarker of neoplastic progression?

✍ Scribed by Tolga Turan; Mina Kalantari; Itzel E. Calleja-Macias; Heather A. Cubie; Kate Cuschieri; Luisa L. Villa; Hanne Skomedal; Hugo A. Barrera-Saldaña; Hans-Ulrich Bernard

Book ID: 113946720
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 663 KB
Volume: 349
Category: Article
ISSN: 0042-6822
DOI: 10.1016/j.virol.2005.12.033

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## Abstract Human papillomavirus‐16 DNA replicates in productive infections in circular form, but is found in most carcinomas integrated into the host cell DNA. Because this transition is essential for carcinogenesis, detailed research is desirable and may help to triage patients with abnormal Pap