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Methylation of p16 CpG islands correlated with metastasis and aggressiveness in papillary thyroid carcinoma

✍ Scribed by Wang, Peng; Pei, Renguang; Lu, Zheming; Rao, Xiaosong; Liu, Baoguo

Book ID
120295570
Publisher
Elsevier Science
Year
2013
Tongue
Chinese
Weight
406 KB
Volume
76
Category
Article
ISSN
1726-4901

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## Abstract The role of aberrant tumor suppressor gene methylation in the aggressiveness of papillary thyroid cancer (PTC) has not been documented. By showing promoter methylation‐induced gene silencing in PTC‐derived cell lines, we first demonstrated the functional consequence of methylation of se