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Methylation of multiple genes as a candidate biomarker in non-small cell lung cancer

✍ Scribed by Youwei Zhang; Rui Wang; Haizhu Song; Guichun Huang; Jun Yi; Yun Zheng; Jinghua Wang; Longbang Chen

Book ID: 116335577
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 481 KB
Volume: 303
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2010.12.011

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## Abstract __TMS1__ (target of methylation‐induced silencing) is a CpG island‐associated gene that functions in the regulation of apoptosis and encodes a caspase recruitment domain, a recently described motif found in apoptotic signaling molecules. Recent evidence suggests that silencing of genes