✦ LIBER ✦

Methylation of MGMT in malignant pleural mesothelioma occurs in a subset of patients and is associated with the T allele of the rs16906252 MGMT promoter SNP

✍ Scribed by Kristensen, Lasse Sommer; Nielsen, Helene Myrtue; Hager, Henrik; Hansen, Lise Lotte

Book ID: 119320396
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 902 KB
Volume: 71
Category: Article
ISSN: 0169-5002
DOI: 10.1016/j.lungcan.2010.05.008

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The T genotype of the MGMT C>T (rs169062

The T genotype of the MGMT C>T (rs16906252) enhancer single-nucleotide polymorphism (SNP) is associated with promoter methylation and longer survival in glioblastoma patients

✍ McDonald, K.L.; Rapkins, R.W.; Olivier, J.; Zhao, L.; Nozue, K.; Lu, D.; Tiwari, 📂 Article 📅 2013 🏛 Elsevier Science 🌐 English ⚖ 626 KB

A specific CpG methylation pattern of th

A specific CpG methylation pattern of the MGMT promoter region associated with reduced MGMT expression in primary colorectal cancers

✍ Klaus K.-F. Herfarth; Thomas P. Brent; Rebecca P. Danam; Joanna S. Remack; Ira J 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 122 KB 👁 2 views

The enzyme O 6 -methylguanine-DNA methyltransferase (MGMT) protects cells from the cytotoxic and mutagenic effects of alkylating agents. Approximately 20% of tumor cell lines lack MGMT activity and are highly sensitive to alkylating agents. In established cancer cell lines, MGMT expression appears t

MicroRNA-137 promoter methylation is ass

MicroRNA-137 promoter methylation is associated with poorer overall survival in patients with squamous cell carcinoma of the head and neck

✍ Scott M. Langevin; Roslyn A. Stone; Clareann H. Bunker; Maureen A. Lyons-Weiler; 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 205 KB 👁 3 views

The −516 C allele in the apolipoprotein

The −516 C allele in the apolipoprotein B100 promoter is associated with low lipid levels and with a low frequency of subclinical atherosclerosis in hypercholesterolemic patients

📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 154 KB

Loss of MTBP expression is associated wi

Loss of MTBP expression is associated with reduced survival in a biomarker-defined subset of patients with squamous cell carcinoma of the head and neck

✍ Nikolina Vlatković; Ashraf El-Fert; Timothy Devling; Arpita Ray-Sinha; David M. 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 590 KB

## Abstract ## BACKGROUND: Recent genetic studies have implicated p53 mutation as a significant risk factor for therapeutic failure in squamous cell carcinoma of the head and neck (SCCHN). However, in a recent meta‐analysis in the literature of p53 from major anatomical subsites (larynx, oral cavi

2P-0396 The −493 T/G polymorphism in the

2P-0396 The −493 T/G polymorphism in the promoter of the microsomal triglyceride transfer protein (MTP): The G allele is associated with elevated levels of LDL-cholesterol only in patients with elevated body mass index (BMI)

✍ Gonbert, S.; Sposito, A.; Turpin, G.; Chapman, J.; Thillet, J. 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 60 KB