Methylation of 4-nitro-3(5)-pyrazolecarboxylic acid
✍ Scribed by Andrzej Regiec; Henryk Mastalarz; Agnieszka Mastalarz; Andrzej Kochel
- Book ID
- 104096383
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- French
- Weight
- 230 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Reactions of 4-nitro-3(5)-pyrazolecarboxylic acid dipotassium salt with different methylating agents in various solvents have been investigated to improve the synthesis of isomeric 1-methyl-4-nitro-3-and -5-pyrazolecarboxylic acids.
📜 SIMILAR VOLUMES
Single-crystal X-ray study T = 293 K Mean '(C±C) = 0.002 A Ê R factor = 0.046 wR factor = 0.145 Data-to-parameter ratio = 16.0 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
The molecules of the title compound, C~5~H~5~N~3~O~4~, are approximately planar. The nitro group makes a dihedral angle of 1.3 (4)° with the plane of the six-membered ring. This coplanar disposition is a reason for the changes in valence angles in the vicinity of the nitro group. Molecules are conne