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Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin

✍ Scribed by Temmerman, Stéphane; Pethe, Kevin; Parra, Marcela; Alonso, Sylvie; Rouanet, Carine; Pickett, Thames; Drowart, Annie; Debrie, Anne-Sophie; Delogu, Giovanni; Menozzi, Franco D


Book ID
109931599
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
578 KB
Volume
10
Category
Article
ISSN
1078-8956

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## A DR17-restricted T cell epitope from a secreted Mycobacterium tuberculosis antigen only binds to DR17 molecules at neutral pH The assembly of peptide-major histocompatability class I1 complexes in vitro is accelerated at low pH, comparable to that found in the intracellular compartments of met